Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13140945 | 1.00 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL7449284 | 0.83 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL29543279 | 0.81 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL1753813 | 0.81 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL18513573 | 0.81 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL14768852 | 0.81 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL7366925 | 0.79 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL18513572 | 0.79 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL7355983 | 0.79 | CYP3A4 (0.50) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 | |
| SCHEMBL12125671 | 0.79 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419962-B2 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20060142214-A1 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142214-A1 | 3,6-bicyclolides | ABCB11, CYP2B6, CYP3A7 | SLC6A3 2823/4885SLC6A2 3602/4885SLC6A4 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.