Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023489 | 0.77 | CHRNB2 (0.54) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL1023383 | 0.75 | CHRNB2 (0.48) | CHRNB2CHRNA4P2RY14 | |
| Hydrochloric Acid SCHEMBL1072684 | 0.74 | CHRNB2 (0.47) | CHRNB2CHRNA4P2RY14 | |
| SCHEMBL1022339 | 0.73 | CHRNB2 (0.52) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL1022337 | 0.73 | CHRNB2 (0.52) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL7809874 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL6993886 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL2881954 | 0.70 | CHRNB2 (0.67) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL12093045 | 0.70 | CHRNB2 (0.67) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL5760094 | 0.69 | DYRK1A (0.40) | DYRK1ACA12ENPP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242419-A1 | AZABICYCLO 3.2.1]OCTANE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046187-A1 | AZABICYCLO[3.2.1]OCTANE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |