Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.55 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.35 |
| ▸ | CDK9 | P50750 | 4/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881954 | 0.82 | CHRNB2 (0.67) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL12093045 | 0.82 | CHRNB2 (0.67) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL7805901 | 0.82 | CHRNB2 (0.54) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL18111494 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL16158125 | 0.81 | CHRNB2 (0.57) | CHRNB2CHRNA4CCNT1CDK9NISCH | |
| SCHEMBL7214949 | 0.80 | CHRNB2 (0.52) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL15359024 | 0.79 | CHRNB2 (0.46) | CHRNB2CHRNA4CCNT1CDK9 | |
| SCHEMBL6577750 | 0.79 | P2RY14 (0.59) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL5194310 | 0.76 | CHRNB2 (0.51) | CHRNB2CHRNA4P2RY14 | |
| SCHEMBL5194296 | 0.76 | CHRNB2 (0.51) | CHRNB2CHRNA4P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | claimed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | claimed |
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | disclosed |