SCHEMBL7455355

SCHEMBL7455355

CCOC(=O)COc1ccccc1C(N)=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.63
MAPT P10636 5/20 0.57
LMNA P02545 3/20 0.57
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
NR1I2 O75469 1/20 0.57
CHRM2 P08172 1/20 0.57
CYP3A4 P08684 1/20 0.57
ADRA2A P08913 1/20 0.57
OPRK1 P41145 1/20 0.57
HTR2B P41595 1/20 0.57
SLC6A3 Q01959 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
USP2 O75604 1/20 0.56
HTT P42858 2/20 0.54
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
CASP3 P42574 1/20 0.52
CASP7 P55210 1/20 0.52
CASP9 P55211 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20150685 0.86 ABCB1 (0.64) ABCB1MAPTLMNAKMT2AMEN1
SCHEMBL9713678 0.86 ABCB1 (0.68) ABCB1MAPTLMNAKMT2AMEN1
SCHEMBL8008468 0.86 ABCB1 (0.64) ABCB1MAPTLMNAUSP2NPC1
SCHEMBL4167809 0.86 ABCB1 (0.64) ABCB1MAPTLMNAUSP2NPC1
SCHEMBL2010417 0.85 USP2 (0.67) ABCB1MAPTLMNAUSP2NPC1
SCHEMBL18702668 0.84 ABCB1 (0.71) ABCB1MAPTLMNAUSP2NPC1
SCHEMBL25044302 0.84 PARP1 (0.58) MAPTLMNAKMT2AMEN1NR1I2
Ethenzamide SCHEMBL27612766 0.83 MAPT (0.68) MAPTLMNAKMT2AMEN1NR1I2
Ethenzamide SCHEMBL25624 0.83 MAPT (0.68) MAPTLMNAKMT2AMEN1NR1I2
SCHEMBL7897849 0.83 ABCB1 (0.61) ABCB1MAPTLMNASLC6A3USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040108-A1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AKTIENGESELLSCHAFT (DE) 2000-10-04 EP claimed
WO-1999032477-A1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-01 WO claimed
EP-1059561-A1 Stabilizer compounds for photothermographic elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 2000-12-13 EP disclosed
EP-1040108-A1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AKTIENGESELLSCHAFT (DE) 2000-10-04 EP disclosed
US-6083681-A Stabilizer compounds for photothermographic elements EASTMAN KODAK COMPANY (US) 2000-07-04 US disclosed
WO-1999032477-A1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed