Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | MPC2 | O95563 | 2/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707014 | 0.89 | PTPN1 (0.64) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6447702 | 0.86 | ALDH1A1 (0.53) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL8182679 | 0.84 | PTPN1 (0.79) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL13524845 | 0.83 | PTPN1 (0.55) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL13847876 | 0.82 | PTPN1 (0.54) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL14262660 | 0.82 | PTPN1 (0.68) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6231739 | 0.82 | PPARA (0.55) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL13846691 | 0.81 | PTPN1 (0.67) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6233368 | 0.81 | PTPN1 (0.67) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6376424 | 0.81 | POLB (0.54) | PTPN1CA2ALDH1A1PPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1133627-C | Intermediate of N-benzyl dioxothiazolidinyl benzoyl amide derivatives, and its prepn. method | ������ҩ��ʽ���� | 2004-01-07 | — | — | CN | disclosed |
| CN-1336366-A | Intermediate of N-benzyl dioxothiazolidinyl benzoyl amide derivatives, and its prepn. method | KYORIN SEIYAKU KK (JP) | 2002-02-20 | — | — | CN | disclosed |
| EP-0846693-B1 | N-BENZYLDIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-01-23 | — | — | EP | disclosed |
| CN-1069901-C | N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 2001-08-22 | — | — | CN | disclosed |
| US-6147101-A | TREATING HYPERGLYCEMIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-6030990-A | ANTIDIABETIC AND -LIPEMIC AGENTS; PARTICULARLY FOR NON-INSULIN DEPENDENT DIABETES MELLITUS, A BLOOD SUGAR-LOWERING DRUG THAT IMPROVES THE INSULIN RESISTANCE AND HAS HIGH SAFETY AND EFFICIENCY | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| US-6001862-A | ADMINISTERING TO A PATIENT SUFFERING FROM NON-INSULIN DEPENDENT DIABETES MELLITUS A N-BENZYLDIOXOTHIAZOLIDYLBENZAMIDE COMPOUND | KYORIN PHARAMEUTICALS CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| CN-1186489-A | N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 1998-07-01 | — | — | CN | disclosed |
| EP-0846693-A1 | N-BENZYLDIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-06-10 | — | — | EP | disclosed |