Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818673 | 0.84 | CCR4 (0.65) | CCR4POLBKMT2ASPHK1NPBWR1 | |
| SCHEMBL2029864 | 0.84 | CCR4 (0.65) | CCR4POLBKMT2ASPHK1NPBWR1 | |
| SCHEMBL29412321 | 0.84 | CCR4 (0.65) | CCR4POLBKMT2ASPHK1NPBWR1 | |
| SCHEMBL2274909 | 0.82 | POLB (0.61) | POLBMEN1KMT2AKDM4ESPHK1 | |
| SCHEMBL2274911 | 0.82 | POLB (0.61) | POLBMEN1KMT2AKDM4ESPHK1 | |
| SCHEMBL7454316 | 0.81 | POLB (0.55) | POLBMEN1KMT2AKDM4ESPHK1 | |
| SCHEMBL21869793 | 0.79 | POLB (0.58) | POLBMEN1KMT2AKDM4ESPHK1 | |
| SCHEMBL7449941 | 0.78 | KDM4E (0.56) | POLBMEN1KMT2AKDM4ESPHK1 | |
| SCHEMBL9650151 | 0.78 | KDM4E (0.56) | POLBMEN1KMT2AKDM4ESPHK1 | |
| SCHEMBL21017403 | 0.77 | L3MBTL1 (0.60) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137412-A4 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1137412-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000033788-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES INC. (US) | 2000-06-15 | — | — | WO | disclosed |