Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28061941 | 0.88 | TSHR (0.58) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL127000 | 0.85 | TSHR (0.65) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29637724 | 0.85 | TSHR (0.65) | TSHRMEN1NPC1RAB9AKMT2A | |
| O-Xylene SCHEMBL9688145 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1CYP1A2ACHE | |
| Phosphine SCHEMBL22634020 | 0.83 | TSHR (0.62) | TSHRMEN1NPC1RAB9AKMT2A | |
| Fluoride SCHEMBL27757467 | 0.83 | TSHR (0.62) | TSHRMEN1NPC1RAB9AKMT2A | |
| Nitrogen SCHEMBL28056541 | 0.80 | TSHR (0.60) | TSHRMEN1NPC1RAB9AKMT2A | |
| Ethylene Glycol SCHEMBL2467929 | 0.79 | TSHR (0.54) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL11667401 | 0.78 | SLC6A2 (0.49) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21546356 | 0.78 | ALDH1A1 (0.47) | TSHRNPC1RAB9AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007024-A1 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | WESTLAKE LONGVIEW CORPORATION | 2002-01-17 | — | — | US | disclosed |