Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.78 |
| ▸ | MMP3 | P08254 | 19/20 | 0.78 |
| ▸ | MMP2 | P08253 | 17/20 | 0.78 |
| ▸ | MMP1 | P03956 | 17/20 | 0.78 |
| ▸ | MMP7 | P09237 | 15/20 | 0.78 |
| ▸ | MMP9 | P14780 | 9/20 | 0.74 |
| ▸ | MMP8 | P22894 | 9/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449727 | 0.91 | MMP3 (0.64) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7082386 | 0.86 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7245718 | 0.85 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7256981 | 0.85 | MMP13 (0.79) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7249960 | 0.85 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7256578 | 0.85 | MMP13 (0.81) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7591455 | 0.85 | MMP13 (0.60) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7251827 | 0.83 | MMP13 (0.77) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7250944 | 0.83 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7252210 | 0.81 | MMP13 (0.81) | MMP13MMP3MMP2MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265863-A1 | HETEROCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070690-A1 | HETEROCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |