Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483449 | 0.83 | FFAR4 (0.48) | RAB9AARMEN1KMT2ACYP19A1 | |
| SCHEMBL30689410 | 0.83 | DRD1 (0.46) | ARCYP19A1MRGPRX4SLC22A12 | |
| SCHEMBL17623897 | 0.78 | AR (0.53) | ALDH1A1SMN1; SMN2ARCYP19A1MRGPRX4 | |
| SCHEMBL16483358 | 0.77 | FFAR4 (0.47) | ARCYP19A1MRGPRX4SLC22A12 | |
| SCHEMBL509379 | 0.77 | AR (0.50) | RAB9AKDM4EALDH1A1ARMEN1 | |
| SCHEMBL7454153 | 0.76 | PPARG (0.48) | RAB9AKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13890508 | 0.75 | AR (0.66) | ARCYP19A1SLC22A12 | |
| SCHEMBL7448098 | 0.75 | MEN1 (0.47) | RAB9AKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13890548 | 0.75 | AR (0.53) | RAB9AKDM4EALDH1A1ARMEN1 | |
| SCHEMBL18957421 | 0.75 | MEN1 (0.56) | RAB9AKDM4EALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920430-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |