Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PYGL | P06737 | 2/20 | 0.42 |
| ▸ | PYGM | P11217 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448098 | 0.87 | MEN1 (0.47) | PPARGMEN1KMT2ARAB9AMAPT | |
| SCHEMBL961426 | 0.82 | PPARG (0.57) | PPARGMEN1KMT2APYGLPYGM | |
| SCHEMBL8460102 | 0.79 | KDR (0.41) | PYGLPYGMMRGPRX4CYP19A1CYP1A2 | |
| SCHEMBL4309752 | 0.79 | SMN1; SMN2 (0.54) | MEN1KMT2ARAB9AMAPTKDM4E | |
| SCHEMBL7456383 | 0.76 | RAB9A (0.49) | MEN1KMT2ARAB9AMRGPRX4MAPT | |
| SCHEMBL958883 | 0.76 | PPARG (0.55) | PPARGMEN1KMT2ARAB9AMAPT | |
| SCHEMBL31227019 | 0.75 | PPARG (0.51) | PPARGMEN1KMT2APYGLPYGM | |
| SCHEMBL4733431 | 0.74 | BACE1 (0.44) | PPARGRAB9ACYP1A2CYP2C19 | |
| SCHEMBL29720129 | 0.72 | KMT2A (0.73) | MEN1KMT2ARAB9AMRGPRX4MAPT | |
| SCHEMBL6798209 | 0.72 | KMT2A (0.73) | MEN1KMT2ARAB9AMRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920430-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |