Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 11/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409383 | 0.91 | HTR6 (0.52) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7410795 | 0.90 | HTR6 (0.51) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7416712 | 0.89 | DRD2 (0.53) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7407733 | 0.88 | DRD2 (0.49) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7412957 | 0.88 | DRD2 (0.52) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7410819 | 0.85 | DRD3 (0.68) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7410827 | 0.81 | PTGDR2 (0.54) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7412035 | 0.81 | HTR6 (0.55) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7409349 | 0.80 | HTR6 (0.56) | DRD2DRD3HTR6PTGDR2TBXA2R | |
| SCHEMBL7410597 | 0.80 | HTR6 (0.57) | DRD2DRD3HTR6PTGDR2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |