Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.60 |
| ▸ | ITGAV | P06756 | 3/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371865 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7856524 | 0.88 | HPSE (0.57) | ITGB3ITGA2BNR1H4PPARGPPARD | |
| SCHEMBL7372805 | 0.86 | MAPT (0.46) | ITGB3ITGA2BNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL7861974 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7458370 | 0.84 | PPARG (0.60) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7373451 | 0.81 | PPARG (0.65) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7380591 | 0.80 | KCNK3 (0.46) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7856484 | 0.79 | KMT2A (0.51) | NR1H4HPSEKMT2ASMN1; SMN2PKM | |
| SCHEMBL7861970 | 0.79 | ITGB3 (0.76) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7457414 | 0.79 | ITGB3 (0.84) | ITGB3ITGA2BITGAVITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-B1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-02-06 | — | — | EP | claimed |