SCHEMBL7457433

SCHEMBL7457433

CCCCCCCC/C=C\CCCCCCCCN[C]=O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.53
FAAH O00519 3/20 0.52
TRPV1 Q8NER1 1/20 0.52
EPHX2 P34913 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1375706 1.00 PPARA (0.53) PPARAFAAHTRPV1EPHX2
SCHEMBL302734 0.87 EPHX1 (0.48) PPARA
SCHEMBL148471 0.87 EPHX1 (0.48) PPARA
SCHEMBL9660696 0.87 EPHX1 (0.48) PPARA
SCHEMBL76962 0.87 EPHX1 (0.48) PPARA
SCHEMBL146003 0.87 EPHX1 (0.48) PPARA
SCHEMBL9661841 0.87 EPHX1 (0.48) PPARA
SCHEMBL149027 0.87 EPHX1 (0.48) PPARA
SCHEMBL10873634 0.87 EPHX1 (0.48) PPARA
SCHEMBL9661664 0.87 EPHX1 (0.48) PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150202179-A1 FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS YISSUM RES DEV CO (IL) 2015-07-23 US claimed
WO-2014013497-A1 FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2014-01-23 WO claimed
CN-110022895-A therapeutic compositions and methods for treating hepatitis B 阿布特斯生物制药公司 2019-07-16 CN disclosed
WO-2014013497-A1 FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2014-01-23 WO disclosed
US-6433223-B1 HYDROXYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2002-08-13 US disclosed
US-6057090-A Silver halide photographic material and hydroxamic acid-based compound used therefor FUJI PHOTO FILM CO., LTD. (JP) 2000-05-02 US disclosed
US-4052214-A COLOR DIFFUSION TRANSFER PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FOR FORMING BOTH POSITIVE TRANSFER DYE IMAGES AND NEGATIVE DYE IMAGES FUJI PHOTO FILM CO., LTD. (JA) 1977-10-04 US disclosed
US-4015989-A Color light-sensitive material with spontaneously developable silver halide emulsion containing desensitizing dye FUJI PHOTO FILM CO., LTD. (JA) 1977-04-05 US disclosed
US-3960569-A Diffusion transfer color film unit with hydroxy substituted alkylene amino development accelerators FUJI PHOTO FILM CO., LTD. (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150202179-A1 FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS ALOX5, FFAR2, FASN PPARA 27/4885FAAH 10/4885TRPV1 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.