SCHEMBL7457487

SCHEMBL7457487

Cc1ccc(S(=O)(=O)OCC#CI)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
STAT3 P40763 1/20 0.40
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CA1 P00915 4/20 0.38
CA9 Q16790 4/20 0.38
CA12 O43570 3/20 0.38
CA2 P00918 3/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
VDR P11473 1/20 0.38
TLR9 Q9NR96 1/20 0.37
CYP2D6 P10635 2/20 0.37
CYP1A2 P05177 1/20 0.37
GLA P06280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7644858 0.89 GAA (0.46) GAASTAT3ALDH1A1CYP3A4CYP2C9
SCHEMBL542839 0.86 GAA (0.43) GAASTAT3ALDH1A1CYP3A4CYP2C9
SCHEMBL4801283 0.84 CYP1A2 (0.44) GAASTAT3ALDH1A1CYP3A4CYP2C9
SCHEMBL11305969 0.83 PKM (0.47) GAAALDH1A1CA1CA2SMN1; SMN2
SCHEMBL11307710 0.83 MEN1 (0.38) ALDH1A1CA1CA9CA12CA2
SCHEMBL11301556 0.83 PLCG1 (0.41) ALDH1A1CA1CA9CA12CA2
SCHEMBL16344942 0.83 GAA (0.41) GAASTAT3ALDH1A1CYP3A4CYP2C9
SCHEMBL1603835 0.83 GAA (0.41) GAASTAT3ALDH1A1CYP3A4CYP2C9
SCHEMBL7456678 0.83 GAA (0.41) GAASTAT3ALDH1A1CYP3A4CYP2C9
SCHEMBL11305460 0.83 ALDH1A1 (0.41) GAAALDH1A1CYP3A4CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1169309-A4 PROPYNYL URACILS LONZA AG (US) 2002-06-05 EP claimed
EP-1169309-A1 PROPYNYL URACILS LONZA INC. (US) 2002-01-09 EP claimed
WO-2000061565-A1 PROPYNYL URACILS LONZA INC. (US) 2000-10-19 WO claimed
JP-59010515-A None JP disclosed
EP-1169309-A4 PROPYNYL URACILS LONZA AG (US) 2002-06-05 EP disclosed
US-6344460-B1 BACTERICIDES, FUNGICIDES, AND PRESERVATIVES LONZA INC. 2002-02-05 US disclosed
EP-1169309-A1 PROPYNYL URACILS LONZA INC. (US) 2002-01-09 EP disclosed
WO-2000061565-A1 PROPYNYL URACILS LONZA INC. (US) 2000-10-19 WO disclosed
US-5354862-A Preparation and the use of halopropargylated cyclic quaternary ammonium compounds as antimicrobial agents ROHM AND HAAS COMPANY (US) 1994-10-11 US disclosed
US-5266567-A Bactericides, fungicides, algicides ROHM AND HAAS COMPANY (US) 1993-11-30 US disclosed
EP-0539114-A2 Halopropargylated cyclic quaternary ammonium compound as antimicrobial agents ROHM AND HAAS COMPANY (US) 1993-04-28 EP disclosed
US-4647572-A Iodoallyl and iodopropargyl substituted tetrazoles and anti-microbial compositions thereof MEIJI SEIKA KAISHA, LTD. (JP) 1987-03-03 US disclosed
EP-0080051-B1 HETEROCYCLIC COMPOUNDS AND ANTIBACTERIAL AND ANTIFUNGAL COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS MEIJI SEIKA KAISHA LTD. (JP) 1986-02-05 EP disclosed
US-4563472-A BACTERICIDES, FUNGICIDES MEIJI SEIKA KAISHA, LTD. (JP) 1986-01-07 US disclosed
US-4520023-A FUNGICIDES, BACTERICIDES, ALGICIDES, SLIMICIDES BAYER AKTIENGESELLSCHAFT (DE) 1985-05-28 US disclosed
EP-0107859-A1 Tetrazole compounds, process for preparing the same and antibacterial and antifungal compositions containing the same as active ingredient MEIJI SEIKA KAISHA LTD. (JP) 1984-05-09 EP disclosed
JP-S5910515-A IMMUNE ADJUSTING AGENT AND ITS PREPARATION MEIJI SEIKA KAISHA LTD 1984-01-20 JP disclosed
EP-0080051-A2 Heterocyclic compounds and antibacterial and antifungal compositions containing the same as active ingredients MEIJI SEIKA KAISHA LTD. (JP) 1983-06-01 EP disclosed
US-4259350-A PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK SANKYO COMPANY LIMITED (JP) 1981-03-31 US disclosed