Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458310 | 1.00 | BCHE (0.59) | BCHEMAOBABL1RIN1KDM4E | |
| SCHEMBL7458320 | 1.00 | BCHE (0.59) | BCHEMAOBABL1RIN1KDM4E | |
| SCHEMBL28474787 | 0.92 | BCHE (0.61) | BCHEABL1RIN1 | |
| SCHEMBL9463731 | 0.91 | ABL1 (0.56) | BCHEMAOBABL1RIN1 | |
| SCHEMBL9463738 | 0.91 | ABL1 (0.56) | BCHEMAOBABL1RIN1 | |
| SCHEMBL27315592 | 0.90 | BCHE (0.61) | BCHEMAOBKDM4E | |
| SCHEMBL8915069 | 0.85 | BCHE (0.57) | BCHEMAOB | |
| SCHEMBL7301577 | 0.85 | BCHE (0.57) | BCHEMAOB | |
| SCHEMBL2893650 | 0.84 | BCHE (0.60) | BCHEMAOB | |
| SCHEMBL9685669 | 0.84 | BCHE (0.60) | BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900787-B1 | PROCESS FOR PREPARING PYRROLIDINE DERIVATIVES | KANEKA CORP (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-6005119-A | Process for preparing pyrrolidine derivatives | KANEKA CORPORATION (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0900787-A1 | PROCESS FOR PREPARING PYRROLIDINE DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-10 | — | — | EP | disclosed |
| US-5187094-A | Using Pseudomonas or Mucor stereospecific esterases for hydrolysis of racemic mixtures of N-benzyl-3-acyloxy-pyrrolidine | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-02-16 | — | — | US | disclosed |