Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301577 | 1.00 | BCHE (0.57) | BCHEMAOBSCN4AMCHR1SIGMAR1 | |
| SCHEMBL7264220 | 0.93 | BCHE (0.67) | BCHEMAOB | |
| SCHEMBL7288369 | 0.92 | BCHE (0.64) | BCHESIGMAR1 | |
| SCHEMBL27315592 | 0.87 | BCHE (0.61) | BCHEMAOBMCHR1SIGMAR1 | |
| SCHEMBL3206960 | 0.87 | BCHE (0.60) | BCHEMAOBSCN4A | |
| SCHEMBL9685669 | 0.87 | BCHE (0.60) | BCHEMAOBSCN4A | |
| SCHEMBL2893650 | 0.87 | BCHE (0.60) | BCHEMAOBSCN4A | |
| SCHEMBL10515058 | 0.86 | BCHE (0.56) | BCHEMAOBMCHR1SIGMAR1 | |
| SCHEMBL7458310 | 0.85 | BCHE (0.59) | BCHEMAOB | |
| SCHEMBL7458302 | 0.85 | BCHE (0.59) | BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168215-B1 | PROCESS FOR PREPARATION OF BARNIDIPINE | USV PRIVATE LTD (IN) | 2020-05-20 | — | — | EP | claimed |
| EP-3168215-A2 | PROCESS FOR PREPARATION OF BARNIDIPINE | USV Private Limited (IN) | 2017-05-17 | — | — | EP | claimed |
| EP-0160451-B1 | DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTER DERIVATIVE ISOMERS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0160451-A2 | Dihydropyridine-3,5-dicarboxylic acid ester derivative isomers, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | claimed |
| EP-3168215-B1 | PROCESS FOR PREPARATION OF BARNIDIPINE | USV PRIVATE LTD (IN) | 2020-05-20 | — | — | EP | disclosed |
| EP-3168215-A2 | PROCESS FOR PREPARATION OF BARNIDIPINE | USV Private Limited (IN) | 2017-05-17 | — | — | EP | disclosed |
| US-5616715-A | SEPARATION OF STEREOISOMERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5463064-A | Vasodilating and hypotensive activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| US-5364872-A | Coronary vasodilators; hypotensive agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0160451-B1 | DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTER DERIVATIVE ISOMERS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0160451-A2 | Dihydropyridine-3,5-dicarboxylic acid ester derivative isomers, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |