Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206960 | 1.00 | BCHE (0.60) | BCHEMAOBACHESCN4A | |
| SCHEMBL2893650 | 1.00 | BCHE (0.60) | BCHEMAOBACHESCN4A | |
| SCHEMBL19038337 | 0.92 | BCHE (0.72) | BCHEMAOBACHE | |
| SCHEMBL4135213 | 0.91 | BCHE (0.67) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL9380707 | 0.90 | BCHE (0.65) | BCHEACHE | |
| SCHEMBL11478274 | 0.89 | BCHE (0.54) | BCHEMAOB | |
| SCHEMBL250507 | 0.88 | BCHE (0.61) | BCHEMAOB | |
| SCHEMBL7301577 | 0.87 | BCHE (0.57) | BCHEMAOBSCN4A | |
| SCHEMBL8915069 | 0.87 | BCHE (0.57) | BCHEMAOBSCN4A | |
| SCHEMBL27315592 | 0.86 | BCHE (0.61) | BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288519-A4 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | — | 1992-04-15 | — | — | EP | disclosed |
| US-4965273-A | Certain 1-tertiary-butyl-naphthyridone carboxylic acid derivatives anti-bacterial agents | BRISTOL-MYERS COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4954507-A | 1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0288519-A1 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | Bristol-Myers Squibb Company (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0266576-A2 | 1-Tert-alkyl-substituted naphthyridine and quinoline carboxylic acids as antibacterial agents | Bristol-Myers Squibb Company (US) | 1988-05-11 | — | — | EP | disclosed |
| WO-1988002627-A1 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-04-21 | — | — | WO | disclosed |