Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743960 | 0.88 | LTA4H (0.67) | LTA4HKCNH2 | |
| SCHEMBL746968 | 0.85 | LTA4H (0.66) | LTA4HKCNH2 | |
| SCHEMBL745043 | 0.83 | LTA4H (0.61) | LTA4HKCNH2 | |
| SCHEMBL3753192 | 0.81 | LTA4H (0.70) | LTA4HKCNH2 | |
| SCHEMBL3748252 | 0.81 | LTA4H (0.70) | LTA4HKCNH2 | |
| SCHEMBL745072 | 0.81 | LTA4H (0.67) | LTA4HKCNH2 | |
| SCHEMBL746080 | 0.79 | LTA4H (0.65) | LTA4HKCNH2 | |
| SCHEMBL3745390 | 0.76 | LTA4H (0.58) | LTA4HKCNH2 | |
| SCHEMBL3745961 | 0.76 | ALDH1A1 (0.52) | LTA4HKCNH2 | |
| SCHEMBL745969 | 0.76 | LTA4H (1.00) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430019-A1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | Janssen Pharmaceutica, N.V. (BE) | 2012-03-21 | — | — | EP | claimed |
| WO-2010132599-A1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-18 | — | — | WO | claimed |