Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461603 | 0.87 | LPAR5 (0.39) | F10F2BRD4BRD2BRD3 | |
| SCHEMBL7459811 | 0.85 | LPAR5 (0.34) | F10F2LPAR5 | |
| SCHEMBL7458152 | 0.82 | NPC1 (0.45) | NPC1RAB9A | |
| SCHEMBL7469056 | 0.81 | LPAR5 (0.30) | LPAR5 | |
| SCHEMBL7466745 | 0.81 | BRD9 (0.36) | F10F2LPAR5NPC1LMNA | |
| SCHEMBL7468313 | 0.80 | PKM (0.39) | F10F2LPAR5LMNA | |
| SCHEMBL7457641 | 0.80 | — | — | |
| SCHEMBL7458109 | 0.79 | HSP90AA1 (0.39) | HSP90AA1F10F2NPC1RAB9A | |
| SCHEMBL7458121 | 0.78 | ESR1 (0.46) | HSP90AA1F10F2NPC1RAB9A | |
| SCHEMBL7465310 | 0.78 | PPARG (0.34) | F10F2LPAR5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |