Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 7/20 | 0.32 |
| ▸ | F2 | P00734 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468314 | 0.90 | POLB (0.35) | PKMF10F2POLBMEN1 | |
| SCHEMBL7459811 | 0.86 | LPAR5 (0.34) | LPAR5F10F2FAAH | |
| SCHEMBL7462485 | 0.84 | MAPT (0.35) | PKMPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7465907 | 0.83 | KDM4E (0.39) | PKMAGERPOLBMEN1KMT2A | |
| SCHEMBL7462493 | 0.83 | KDM4E (0.39) | PKMAGERPOLBMEN1KMT2A | |
| SCHEMBL7465900 | 0.83 | PTGDR2 (0.39) | PKMKDM4EMAPTPPARDPPARA | |
| SCHEMBL7469056 | 0.82 | LPAR5 (0.30) | LPAR5 | |
| SCHEMBL7453836 | 0.81 | PKM (0.39) | PKMAGERPOLBALDH1A1PPARD | |
| SCHEMBL7459329 | 0.80 | HSP90AA1 (0.33) | LPAR5F10F2LMNA | |
| SCHEMBL7466745 | 0.80 | BRD9 (0.36) | LPAR5F10F2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |