SCHEMBL7459339

SCHEMBL7459339

Cc1cc(C)c(B(c2cc(Br)cc(B(c3c(C)cc(C)cc3C)c3c(C)cc(C)cc3C)c2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7461325 0.96 RAPGEF4 (0.38) RAPGEF4
SCHEMBL5553797 0.89 RAPGEF4 (0.43) RAPGEF4
SCHEMBL23578512 0.84 RAPGEF4 (0.42) RAPGEF4
SCHEMBL7534862 0.82 KDM4E (0.33) RAPGEF4
SCHEMBL5907929 0.81 RAPGEF4 (0.50) RAPGEF4
SCHEMBL15082304 0.80 RAPGEF4 (0.50) RAPGEF4
SCHEMBL7457901 0.78 RAPGEF4 (0.44) RAPGEF4
SCHEMBL22872051 0.77 RAPGEF4 (0.50) RAPGEF4
SCHEMBL12551743 0.77 RAPGEF4 (0.34) RAPGEF4
SCHEMBL85680 0.77 RAPGEF4 (0.42) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775706-B1 Borates photoinitiators from polyboranes CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
EP-1203999-A2 Photoinitiator comprising a borane and an electron donating compound Ciba SC Holding AG (CH) 2002-05-08 EP disclosed
US-6057078-A PHOTOGRAPHY CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
US-5807905-A POLYMERIZATION OF UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
EP-0775706-A2 Borates photoinitiators from polyboranes Ciba SC Holding AG (CH) 1997-05-28 EP disclosed