SCHEMBL85680

SCHEMBL85680

Cc1cc(C)c(B(c2ccc(B(c3c(C)cc(C)cc3C)c3c(C)cc(C)cc3C)cc2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 13/20 0.42
FFAR4 Q5NUL3 2/20 0.36
CA2 P00918 1/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35
TRPV6 Q9H1D0 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PSMB5 P28074 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22146594 0.95 RAPGEF4 (0.45) RAPGEF4FFAR4CA2LPLLIPG
SCHEMBL7458255 0.93 RAPGEF4 (0.37) RAPGEF4FFAR4CA2LPLLIPG
SCHEMBL85808 0.93 RAPGEF4 (0.37) RAPGEF4FFAR4CA2LPLLIPG
SCHEMBL14804397 0.90 RAPGEF4 (0.45) RAPGEF4FFAR4CA2LPLLIPG
SCHEMBL23150833 0.89 FFAR4 (0.44) RAPGEF4FFAR4ORAI1ORAI2ORAI3
SCHEMBL16051086 0.89 ACHE (0.42) RAPGEF4TDP1
SCHEMBL7458913 0.89 FFAR4 (0.43) RAPGEF4FFAR4ORAI1ORAI2ORAI3
SCHEMBL10100950 0.89 ESR1 (0.36) RAPGEF4FFAR4PSMB5
SCHEMBL5907929 0.89 RAPGEF4 (0.50) RAPGEF4FFAR4CA2CYP2A6
SCHEMBL17866557 0.89 FFAR4 (0.44) RAPGEF4FFAR4ORAI1ORAI2ORAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666851-A1 LIGHT-ACCUMULATING COMPOSITION, LIGHT-ACCUMULATING ELEMENT AND WAVELENGTH CONTROL METHOD Okinawa Institute of Science and Technology School Corporation (JP) 2020-06-17 EP disclosed
US-20200165516-A1 LONG-PERSISTENT LUMINESCENT COMPOSITION, LONG-PERSISTENT LUMINESCENT DEVICE AND WAVELENGTH CONTROL METHOD OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2020-05-28 US disclosed
WO-2019189045-A1 PHOSPHORESCENT SUBSTANCE AND PHOSPHORESCENT ELEMENT 国立大学法人九州大学 2019-10-03 WO disclosed
EP-2243177-B1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC (US) 2019-05-15 EP disclosed
EP-2396801-B1 OLED DEVICE WITH FLUORANTHENE-MACROCYCLIC MATERIALS GLOBAL OLED TECHNOLOGY LLC (US) 2018-05-23 EP disclosed
EP-2232612-B1 OLED DEVICE EMPLOYING ALKALI METAL CLUSTER COMPOUNDS GLOBAL OLED TECHNOLOGY LLC (US) 2017-02-08 EP disclosed
US-8900722-B2 OLED device employing alkali metal cluster compounds GLOBAL OLED TECHNOLOGY LLC (US) 2014-12-02 US disclosed
US-8900722-B2 OLED device employing alkali metal cluster compounds GLOBAL OLED TECHNOLOGY LLC (US) 2014-12-02 US disclosed
EP-2218121-B1 OLED DEVICE WITH FLUORANTHENE ELECTRON TRANSPORT MATERIALS GLOBAL OLED TECHNOLOGY LLC (US) 2014-11-26 EP disclosed
US-8431242-B2 OLED device with certain fluoranthene host GLOBAL OLED TECHNOLOGY, LLC. (US) 2013-04-30 US disclosed
US-7279603-B2 Boron and aluminum compounds in electronic components MERCK PATENT GMBH (DE) 2007-10-09 US disclosed
US-20060241321-A1 Use of boron and aluminium compounds in electronic components COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-10-26 US disclosed
US-7060369-B2 Use of boron and aluminum compounds in electronic components COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-06-13 US disclosed
US-20040058194-A1 Use of boron and aluminium compounds in electronic components MERCK PATENT GMBH (DE) 2004-03-25 US disclosed
EP-1217668-A1 Use of boron and aluminium compounds in electronic devices Covion Organic Semiconductors GmbH (DE) 2002-06-26 EP disclosed
EP-0775706-B1 Borates photoinitiators from polyboranes CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
EP-1203999-A2 Photoinitiator comprising a borane and an electron donating compound Ciba SC Holding AG (CH) 2002-05-08 EP disclosed
US-6057078-A PHOTOGRAPHY CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
US-5807905-A POLYMERIZATION OF UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
EP-0775706-A2 Borates photoinitiators from polyboranes Ciba SC Holding AG (CH) 1997-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241321-A1 Use of boron and aluminium compounds in electronic components SLCO4C1, SLC43A3, OSBP2 RAPGEF4 659/4885FFAR4 3398/4885CA2 1380/4885
US-20040058194-A1 Use of boron and aluminium compounds in electronic components SLCO4C1, SLC43A3, OSBP2 RAPGEF4 659/4885FFAR4 3398/4885CA2 1380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.