Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458701 | 1.00 | MEN1 (0.45) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL7452372 | 0.88 | LMNA (0.41) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL7454025 | 0.88 | LMNA (0.41) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL7257123 | 0.85 | HPGD (0.44) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL7454176 | 0.85 | HPGD (0.44) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL6947458 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL6950290 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL7463870 | 0.81 | HPGD (0.46) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL7456216 | 0.81 | HPGD (0.46) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL25342645 | 0.80 | EPHX1 (0.50) | MEN1KMT2AHPGDCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930292-B1 | PROCESS FOR PREPARING BETA-AMINO-ALPHA-HYDROXY ACID DERIVATIVES | KANEKA CORP (JP) | 2002-10-16 | — | — | EP | claimed |