Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.35 |
| ▸ | CALML3 | P27482 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462586 | 0.90 | MAOA (0.32) | MAOACALML3GRM2MAOB | |
| SCHEMBL7837740 | 0.90 | CALML3 (0.35) | MAOACALML3CYP2C19CYP2C9GRM2 | |
| SCHEMBL7846614 | 0.85 | MAOA (0.50) | MAOACALML3MAOB | |
| SCHEMBL7837804 | 0.85 | MAOA (0.38) | MAOACALML3CYP2C19CYP3A4 | |
| SCHEMBL374787 | 0.84 | MAOA (0.35) | MAOACALML3CYP2C19CYP2C9GRM2 | |
| Posizolid SCHEMBL3039615 | 0.80 | MAOA (0.34) | MAOACALML3CYP2C19CYP2C9GRM2 | |
| Posizolid SCHEMBL374786 | 0.80 | MAOA (0.34) | MAOACALML3CYP2C19CYP2C9GRM2 | |
| Posizolid SCHEMBL14286008 | 0.80 | MAOA (0.34) | MAOACALML3CYP2C19CYP2C9GRM2 | |
| Posizolid SCHEMBL7079325 | 0.80 | MAOA (0.34) | MAOACALML3CYP2C19CYP2C9GRM2 | |
| SCHEMBL7466925 | 0.80 | GRM2 (0.39) | MAOAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237895-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | AstraZeneca AB (SE) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001040236-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | ASTRAZENECA AB (SE) | 2001-06-07 | — | — | WO | disclosed |