Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459673 | 0.90 | MAOA (0.35) | CALML3MAOAGRM2CYP2C9CYP2C19 | |
| SCHEMBL7843707 | 0.85 | MAOA (0.51) | CALML3MAOAMAOB | |
| SCHEMBL7462586 | 0.84 | MAOA (0.32) | CALML3MAOAGRM2MAOB | |
| SCHEMBL7466925 | 0.84 | GRM2 (0.39) | MAOAGRM2 | |
| SCHEMBL5229382 | 0.81 | GRM2 (0.37) | CALML3MAOAGRM2 | |
| SCHEMBL12674052 | 0.81 | GRM2 (0.37) | CALML3MAOAGRM2 | |
| Hydrochloric Acid SCHEMBL7081708 | 0.81 | GRM2 (0.37) | CALML3MAOAGRM2 | |
| Hydrochloric Acid SCHEMBL7081703 | 0.81 | GRM2 (0.37) | CALML3MAOAGRM2 | |
| SCHEMBL7084805 | 0.79 | F10 (0.39) | CALML3MAOAGRM2CYP2C9CYP2C19 | |
| SCHEMBL7837804 | 0.78 | MAOA (0.38) | CALML3MAOACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082323-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca UK Limited (GB) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999064417-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |