Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467602 | 0.90 | GAA (0.41) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7444301 | 0.90 | GAA (0.41) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7439750 | 0.88 | ITGB3 (0.39) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7459675 | 0.87 | MEN1 (0.37) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7437047 | 0.87 | ITGB3 (0.38) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7459678 | 0.85 | KMT2A (0.41) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7496508 | 0.85 | ITGB3 (0.49) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7452051 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTITGB3 | |
| SCHEMBL7446606 | 0.84 | STS (0.42) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL7438522 | 0.83 | GAA (0.40) | MEN1KMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |