Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.78 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453889 | 0.89 | MCHR1 (0.80) | MCHR1DRD3SLC18A3CCR3CCR1 | |
| SCHEMBL7463098 | 0.88 | MCHR1 (1.00) | MCHR1SLC18A3CCR3CCR1SIGMAR1 | |
| SCHEMBL7459555 | 0.87 | MCHR1 (0.86) | MCHR1CACNA1GSLC18A3CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7463694 | 0.87 | MCHR1 (0.98) | MCHR1SLC18A3CCR3CCR1SIGMAR1 | |
| SCHEMBL7459747 | 0.86 | MCHR1 (0.78) | MCHR1CACNA1GKCNH2CCR3CCR1 | |
| SCHEMBL7459727 | 0.85 | MCHR1 (0.82) | MCHR1CACNA1GCCR3CCR1CCR2 | |
| Hydrochloric Acid SCHEMBL7462015 | 0.85 | MCHR1 (0.77) | MCHR1CACNA1GKCNH2CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7466901 | 0.85 | MCHR1 (0.85) | MCHR1CCR3CCR1CCR2SIGMAR1 | |
| SCHEMBL7462063 | 0.84 | MCHR1 (0.89) | MCHR1CCR3CCR1SIGMAR1 | |
| SCHEMBL7460707 | 0.83 | MCHR1 (0.76) | MCHR1SLC18A3CCR3CCR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |