⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27987148 | 0.70 | — | — | |
| SCHEMBL5679648 | 0.70 | — | — | |
| Phosphoric Acid SCHEMBL22371896 | 0.70 | — | — | |
| SCHEMBL11054896 | 0.68 | — | — | |
| SCHEMBL31707295 | 0.68 | — | — | |
| Foscarnet SCHEMBL8647698 | 0.67 | BLM (0.41) | — | |
| Foscarnet SCHEMBL15531347 | 0.67 | BLM (0.41) | — | |
| Foscarnet SCHEMBL23633 | 0.67 | — | — | |
| SCHEMBL534550 | 0.67 | MMP2 (0.39) | — | |
| SCHEMBL7820 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563514-A | Highly specific genome editing using chemically modified guide RNAs | 安捷伦科技有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-107922949-A | Compounds and methods for CRISPR/CAS-based genome editing by homologous recombination | 安捷伦科技有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-114375334-A | Engineered CasX system | 斯克里贝治疗公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-107250148-B | Guide RNAs with chemical modifications | 安捷伦科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-109563514-A | Highly specific genome editing using chemically modified guide RNAs | 安捷伦科技有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-107922949-A | Compounds and methods for CRISPR/CAS-based genome editing by homologous recombination | 安捷伦科技有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107250148-A | Guide RNA with chemical modification | 安捷伦科技有限公司 | 2017-10-13 | — | — | CN | disclosed |
| EP-1094821-A4 | PREPARATION AND USE OF SULFUR-CONTAINING PHOSPHONOFORMATE DERIVATIVES AND ANALOGS | UNIV SOUTHERN CALIFORNIA (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-1094821-A1 | PREPARATION AND USE OF SULFUR-CONTAINING PHOSPHONOFORMATE DERIVATIVES AND ANALOGS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002566-A1 | PREPARATION AND USE OF SULFUR-CONTAINING PHOSPHONOFORMATE DERIVATIVES AND ANALOGS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2000-01-20 | — | — | WO | disclosed |