SCHEMBL7459802

SCHEMBL7459802

COC(=O)c1scc(F)c1OS(=O)(=O)Cl

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.42
KDM4E B2RXH2 5/20 0.41
KMT2A Q03164 2/20 0.39
PTPN1 P18031 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 3/20 0.36
TSHR P16473 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7478305 0.84 COMT (0.34) KCNH2PTPN1HPGDALDH1A1LMNA
SCHEMBL7470407 0.84 MAPT (0.45) KDM4EKMT2AMAPTHPGDALDH1A1
SCHEMBL7465050 0.83 KMT2A (0.46) KDM4EKMT2AMAPTLMNAPKM
SCHEMBL7469821 0.83 KDM4E (0.42) KDM4EKMT2APTPN1MAPTHPGD
SCHEMBL7472790 0.83 KDM4E (0.42) KCNH2KDM4EKMT2APTPN1MAPT
SCHEMBL7468266 0.82 KDM4E (0.40) KCNH2KDM4EKMT2APTPN1MAPT
SCHEMBL7469898 0.82 STS (0.37) KDM4EKMT2AMAPTHPGDALDH1A1
SCHEMBL7473517 0.82 KDM4E (0.41) KDM4EKMT2APTPN1MAPTHPGD
SCHEMBL7469016 0.81 KDM4E (0.42) KCNH2KDM4EKMT2APTPN1MAPT
SCHEMBL7464794 0.81 KDM4E (0.44) KDM4EKMT2AMAPTLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed