SCHEMBL7469898

SCHEMBL7469898

CCCOC(=O)c1scc(F)c1OS(=O)(=O)Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 3/20 0.37
LMNA P02545 5/20 0.36
MAPT P10636 2/20 0.36
THRB P10828 2/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 1/20 0.36
COMT P21964 2/20 0.36
TP53 P04637 2/20 0.35
ESR1 P03372 1/20 0.34
CHRM1 P11229 1/20 0.34
TSHR P16473 1/20 0.34
SLC6A2 P23975 1/20 0.34
KDR P35968 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7470407 0.89 MAPT (0.45) LMNAMAPTTHRBALDH1A1HPGD
SCHEMBL7466963 0.85 STS (0.38) STSLMNAMAPTTHRBALDH1A1
SCHEMBL7469073 0.85 STS (0.38) STSLMNAMAPTTHRBALDH1A1
SCHEMBL7474149 0.85 STS (0.38) STSLMNAMAPTALDH1A1HPGD
SCHEMBL7465252 0.85 STS (0.38) STSLMNAMAPTTHRBALDH1A1
SCHEMBL7463491 0.84 STS (0.34) STSLMNAMAPTTHRBALDH1A1
SCHEMBL7464814 0.84 STS (0.35) STSLMNAMAPTTHRBALDH1A1
SCHEMBL7471765 0.83 POLB (0.39) STSLMNAMAPTALDH1A1HPGD
SCHEMBL7471848 0.82 STS (0.36) STSLMNAMAPTALDH1A1HPGD
SCHEMBL7459802 0.82 KCNH2 (0.42) LMNAMAPTALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed