SCHEMBL7470407

SCHEMBL7470407

CCOC(=O)c1scc(F)c1OS(=O)(=O)Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.45
LMNA P02545 4/20 0.45
THRB P10828 2/20 0.45
TP53 P04637 2/20 0.43
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
GAA P10253 2/20 0.38
HSD17B10 Q99714 2/20 0.38
PRKCZ Q05513 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GLA P06280 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
PKM P14618 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7469898 0.89 STS (0.37) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7466240 0.86 MAPT (0.39) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7470040 0.84 ALDH1A1 (0.41) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7469012 0.84 MAPT (0.41) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7472780 0.84 MAPT (0.39) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7459802 0.84 KCNH2 (0.42) MAPTLMNAALDH1A1KDM4EHPGD
SCHEMBL7467922 0.83 MAPT (0.37) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7475408 0.83 MAPK8 (0.40) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7463597 0.82 MAPT (0.44) MAPTLMNATHRBTP53ALDH1A1
SCHEMBL7477592 0.81 LMNA (0.37) MAPTLMNATHRBTP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed