Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563535 | 0.79 | KMT2A (0.37) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL2360743 | 0.72 | KMT2A (0.43) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL28818918 | 0.70 | KMT2A (0.48) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL22007496 | 0.69 | KMT2A (0.39) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL7459879 | 0.68 | CA12 (0.43) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL27470889 | 0.66 | KMT2A (0.39) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL3835020 | 0.66 | LMNA (0.43) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL8741557 | 0.66 | LMNA (0.43) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL296106 | 0.65 | LMNA (0.48) | KMT2ALMNATHRBCYP2C19TYMP | |
| SCHEMBL27795012 | 0.65 | KMT2A (0.44) | KMT2ALMNATHRBCYP2C19TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359120-B1 | REACTING ALKYLENE DIAMINE WITH HALOKETONE TO PROVIDE AN ALKYLENE DIAMINEDIKETONE WHICH IS CONVERTED TO ALKYLENE DIAMINEDIOXIME; OR REACTING ALKYLENE DIAMINE WITH FIRST HALOKETONE AND REACTING WITH SECOND HALOKETONE | BRACCO INTERNATIONAL B.V. (NL) | 2002-03-19 | — | — | US | disclosed |
| US-6184361-B1 | Rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 2001-02-06 | — | — | US | disclosed |