Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459874 | 0.79 | KMT2A (0.38) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL28818918 | 0.68 | KMT2A (0.48) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL9060085 | 0.67 | KMT2A (0.43) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL2360743 | 0.65 | KMT2A (0.43) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL9762548 | 0.65 | KMT2A (0.43) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL10400098 | 0.64 | KMT2A (0.45) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL27795012 | 0.64 | KMT2A (0.44) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL3131540 | 0.63 | KMT2A (0.41) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL4136129 | 0.62 | KMT2A (0.38) | KMT2ALMNATHRBCYP2C19 | |
| Misonidazole SCHEMBL51943 | 0.62 | KMT2A (0.66) | KMT2ALMNATHRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808091-A | DIAGNOSTIC IMAGING AGENT | BRACCO INTERNATIONAL B.V. | 1998-09-15 | — | — | US | disclosed |
| US-5741912-A | DIAGNOSIS, THERAPY | BRACCO INTERNATIONAL B.V. | 1998-04-21 | — | — | US | disclosed |
| US-5688487-A | Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 1997-11-18 | — | — | US | disclosed |