Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363778 | 0.95 | ALDH1A1 (0.53) | EEF2KALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7365176 | 0.85 | ALDH1A1 (0.45) | EEF2KALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29024564 | 0.79 | EEF2K (0.76) | EEF2KALDH1A1CNR1CNR2ADAMTS4 | |
| SCHEMBL7194134 | 0.78 | MAPT (0.59) | EEF2KALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3837360 | 0.78 | ALDH1A1 (0.54) | EEF2KALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29024588 | 0.77 | EEF2K (0.62) | EEF2KALDH1A1CNR1CNR2MMP13 | |
| SCHEMBL3839370 | 0.76 | ALDH1A1 (0.76) | EEF2KALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7360595 | 0.76 | PDCD1 (0.50) | CNR2L3MBTL1PDCD1CD274KCNA5 | |
| SCHEMBL7460113 | 0.76 | BACE1 (0.52) | EEF2KCNR1CNR2MMP13ADAMTS4 | |
| SCHEMBL6329440 | 0.75 | PDCD1 (0.49) | CNR2PDCD1CD274KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |