Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | EEF2K | O00418 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460104 | 0.95 | EEF2K (0.59) | ALDH1A1MAPTEEF2KKMT2AMEN1 | |
| SCHEMBL7365176 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTEEF2KKMT2AMEN1 | |
| SCHEMBL29024564 | 0.78 | EEF2K (0.76) | ALDH1A1EEF2KCNR1CNR2ADAMTS4 | |
| SCHEMBL11563720 | 0.78 | KMT2A (0.52) | ALDH1A1MAPTKMT2AMEN1ATM | |
| SCHEMBL7194134 | 0.77 | MAPT (0.59) | ALDH1A1MAPTEEF2KKMT2AMEN1 | |
| SCHEMBL3837360 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTEEF2KKMT2AMEN1 | |
| SCHEMBL7450718 | 0.76 | CTSL (0.52) | PSMB8PSMB5CNR1CNR2ADAMTS4 | |
| SCHEMBL29024588 | 0.76 | EEF2K (0.62) | ALDH1A1EEF2KCNR1CNR2ADAMTS4 | |
| SCHEMBL27228886 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTEEF2KKMT2AMEN1 | |
| SCHEMBL3839370 | 0.76 | ALDH1A1 (0.76) | ALDH1A1MAPTEEF2KKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |