Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4069270 | 0.86 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL7458244 | 0.74 | MAPT (0.43) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL19465445 | 0.74 | MAPT (0.40) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL19012881 | 0.74 | MAPT (0.40) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL2967698 | 0.73 | KDM4E (0.50) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL19465416 | 0.71 | FAAH (0.37) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL10465761 | 0.71 | CYP11B1 (0.41) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL2970875 | 0.71 | KDM4E (0.47) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL4204967 | 0.70 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL12329 | 0.70 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| US-6156700-A | 3-(1,2-Benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione herbicidal agents | AMERICAN CYANMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1999014216-A1 | SUBSTITUTED 3(-1,2-BENZISOTHIAZOL OR ISOXAZOL-5 YL)-SUBSTITUTED PYRIMIDINE AS HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |