Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465445 | 0.84 | MAPT (0.40) | FAAHMGLLMAPTKDM4EALDH1A1 | |
| SCHEMBL19012881 | 0.81 | MAPT (0.40) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL22388548 | 0.72 | SMN1; SMN2 (0.38) | FAAHMGLLMAPTALDH1A1CNR2 | |
| SCHEMBL22388545 | 0.72 | KDM4E (0.39) | MAPTKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL4069270 | 0.72 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL22388595 | 0.71 | FAAH (0.52) | FAAHMGLLCNR2CNR1LMNA | |
| SCHEMBL28856577 | 0.71 | ACHE (0.42) | FAAHMGLLMAPTKDM4EALDH1A1 | |
| SCHEMBL25101361 | 0.70 | CYP2C19 (0.49) | FAAHMGLLMAPTKDM4EALDH1A1 | |
| SCHEMBL23453144 | 0.69 | CASR (0.45) | ALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL22388544 | 0.68 | CNR2 (0.33) | MAPTKDM4ECNR2CNR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11071731-B2 | Allosteric modulators of the mu opioid receptor | Chiromics, LLC (US) | 2021-07-27 | — | — | US | disclosed |
| US-20200276177-A1 | Allosteric Modulators of the Mu Opioid Receptor | Chiromics, LLC (US) | 2020-09-03 | — | — | US | disclosed |
| US-9790237-B2 | Processes for making alkylated arylpiperazine and alkylated arylpiperidine compounds including novel intermediates | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200276177-A1 | Allosteric Modulators of the Mu Opioid Receptor | OPRM1, OPRK1, OPRD1 | FAAH 252/4885MGLL 1367/4885MAPT 1331/4885 |
| US-11071731-B2 | Allosteric modulators of the mu opioid receptor | OPRM1, OPRK1, OPRD1 | FAAH 252/4885MGLL 1367/4885MAPT 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.