Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 5/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466666 | 0.94 | MCHR1 (0.47) | MCHR1SLC18A3CCR2DRD2 | |
| SCHEMBL7463962 | 0.94 | MCHR1 (0.47) | MCHR1SIGMAR1 | |
| SCHEMBL7463862 | 0.89 | MCHR1 (0.42) | MCHR1KCNA3CCR2 | |
| SCHEMBL7463105 | 0.87 | MCHR1 (0.65) | MCHR1SLC18A3HTR7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7463703 | 0.86 | MCHR1 (0.64) | MCHR1SLC18A3HTR7SIGMAR1 | |
| SCHEMBL7465427 | 0.85 | MCHR1 (0.51) | MCHR1SLC18A3HTR7SIGMAR1 | |
| SCHEMBL7453896 | 0.85 | MCHR1 (0.53) | MCHR1SLC18A3HTR7SIGMAR1 | |
| SCHEMBL7464981 | 0.84 | CACNA1G (0.41) | MCHR1CCR2ADRA1DADRA1AADRA1B | |
| SCHEMBL7459564 | 0.84 | MCHR1 (0.57) | MCHR1SLC18A3CCR2MAOAMAOB | |
| SCHEMBL7462069 | 0.83 | MCHR1 (0.59) | MCHR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |