Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463862 | 0.95 | MCHR1 (0.42) | CACNA1GKCNH2OPRL1CCR2MCHR1 | |
| SCHEMBL7461089 | 0.94 | CCR3 (0.39) | CACNA1GKCNH2OPRL1MCHR1CHRM4 | |
| SCHEMBL7461824 | 0.92 | CACNA1G (0.51) | CACNA1GKCNH2CCR2MCHR1DRD4 | |
| SCHEMBL7466666 | 0.91 | MCHR1 (0.47) | CACNA1GOPRL1CCR2MCHR1DRD2 | |
| SCHEMBL7460719 | 0.84 | MCHR1 (0.53) | CCR2MCHR1DRD2ADRA1DADRA1A | |
| SCHEMBL7463245 | 0.83 | MCHR1 (0.53) | CACNA1GKCNH2OPRL1MCHR1CHRM4 | |
| Hydrochloric Acid SCHEMBL7465687 | 0.83 | MCHR1 (0.52) | CACNA1GKCNH2OPRL1MCHR1CHRM4 | |
| SCHEMBL7463962 | 0.83 | MCHR1 (0.47) | MCHR1CCR1CCR3 | |
| SCHEMBL7464970 | 0.81 | MCHR1 (0.55) | CACNA1GKCNH2OPRL1CCR2MCHR1 | |
| SCHEMBL7455821 | 0.78 | KDM1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |