Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7455613 | 0.99 | IMPDH2 (0.42) | IMPDH2CYP2A6KCNH2TDO2MAPT | |
| SCHEMBL7460881 | 0.86 | IMPDH2 (0.41) | IMPDH2CYP2A6KCNH2TDO2MAPT | |
| SCHEMBL6570840 | 0.83 | ALDH1A1 (0.36) | MAPTMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7461528 | 0.82 | IMPDH2 (0.40) | IMPDH2CYP2A6KCNH2TDO2MAPT | |
| SCHEMBL7461381 | 0.81 | IMPDH2 (0.39) | IMPDH2CYP2A6KCNH2TDO2MAPT | |
| SCHEMBL7086041 | 0.81 | IMPDH2 (0.41) | IMPDH2MAPTMEN1KMT2ACHEK2 | |
| SCHEMBL6571885 | 0.80 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7456014 | 0.80 | CYP2A6 (0.39) | IMPDH2CYP2A6KCNH2TDO2MAPT | |
| SCHEMBL7457589 | 0.80 | KCNH2 (0.36) | IMPDH2CYP2A6KCNH2TDO2MAPT | |
| SCHEMBL6571486 | 0.79 | USP7 (0.40) | MAPTMEN1ALOX15KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963982-B1 | New diaminobenzene derivatives and these componends containing colouring agents | WELLA AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |
| EP-0963982-A2 | New diaminobenzene derivatives and these componends containing colouring agents | Wella Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |