Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532122 | 0.89 | NR4A2 (0.40) | CYP2C9SMN1; SMN2LMNATSHRAPEX1 | |
| Quinoxyfen SCHEMBL28247243 | 0.87 | RET (0.42) | CYP2C9CYP1A2CYP3A4CYP2C19EGFR | |
| Quinoxyfen SCHEMBL22257 | 0.87 | RET (0.42) | CYP2C9CYP1A2CYP3A4CYP2C19EGFR | |
| Quinoxyfen SCHEMBL1974400 | 0.85 | RET (0.41) | CYP2C9CYP1A2CYP3A4CYP2C19EGFR | |
| Quinoxyfen SCHEMBL7471425 | 0.85 | RET (0.41) | CYP2C9CYP1A2CYP3A4CYP2C19EGFR | |
| SCHEMBL7461330 | 0.84 | RHEB (0.46) | ALDH1A1EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL7466633 | 0.84 | EGFR (0.54) | ALDH1A1NPSR1EGFRSMN1; SMN2LMNA | |
| SCHEMBL7460172 | 0.83 | MERTK (0.42) | EGFRERBB2ERBB3ERBB4KMT2A | |
| SCHEMBL7050110 | 0.81 | EGFR (0.41) | EGFRERBB2ERBB3ERBB4MEN1 | |
| Quinoxyfen SCHEMBL28210064 | 0.80 | RET (0.40) | EGFRERBB2KITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-A2 | Quinoline, quinazoline, and cinnoline fungicides | DowElanco (US) | 1989-08-02 | — | — | EP | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0326330-A2 | Quinoline, quinazoline, and cinnoline fungicides | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |