Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxyfen SCHEMBL22257 | 1.00 | RET (0.42) | RETMAPTL3MBTL1METAXL | |
| Quinoxyfen SCHEMBL1974400 | 0.99 | RET (0.41) | RETMAPTL3MBTL1METAXL | |
| Quinoxyfen SCHEMBL7471425 | 0.99 | RET (0.41) | RETMAPTL3MBTL1METAXL | |
| Quinoxyfen SCHEMBL28210064 | 0.92 | RET (0.40) | RETMAPTL3MBTL1METAXL | |
| SCHEMBL7460965 | 0.87 | PLAU (0.46) | PDGFRACYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7532122 | 0.85 | NR4A2 (0.40) | MAPTL3MBTL1CYP2C9LMNATSHR | |
| SCHEMBL7460529 | 0.84 | SLC6A2 (0.43) | MAPTMETAXLMERTKKDR | |
| SCHEMBL27313912 | 0.84 | L3MBTL1 (0.40) | RETMAPTL3MBTL1METAXL | |
| SCHEMBL7464948 | 0.83 | TRPA1 (0.45) | RETMETKDRPDGFRATRPA1 | |
| SCHEMBL7050110 | 0.83 | EGFR (0.41) | KDRTRPA1EGFRERBB2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689927-A | A kind of quinoxyfen and its synthetic method | 陕西恒润化学工业有限公司 | 2018-10-23 | — | — | CN | disclosed |