SCHEMBL7460974

SCHEMBL7460974

CC(O)c1cccc(NCc2cscc2-c2cc(N)ccc2N)c1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 3/20 0.37
KDM4E B2RXH2 1/20 0.36
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
FADS1 O60427 1/20 0.31
EGFR P00533 1/20 0.31
PIK3CA P42336 1/20 0.31
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7455630 0.99 MEN1 (0.37) MEN1KMT2ALMNAKDM4ETSHR
SCHEMBL6266462 0.83 MEN1 (0.44) MEN1KMT2ALMNAKDM4ETSHR
Hydrochloric Acid SCHEMBL6270369 0.82 MEN1 (0.43) MEN1KMT2ALMNAKDM4ETSHR
SCHEMBL7460493 0.82 ADRA2B (0.37) MEN1KMT2ALMNAKDM4EMAPT
SCHEMBL7452886 0.81 ADRA2B (0.33) MEN1KMT2ALMNAKDM4ETSHR
SCHEMBL7463058 0.81 MAPT (0.42) MEN1KMT2ALMNAKDM4EMAPT
SCHEMBL7461007 0.81 BCHE (0.43) MEN1KMT2AKDM4EMAPTALOX12
Hydrochloric Acid SCHEMBL7455787 0.81 ADRA2B (0.36) MEN1KMT2ALMNAKDM4EMAPT
Hydrochloric Acid SCHEMBL7462157 0.81 ADRA2B (0.33) MEN1KMT2AKDM4EMAPTEGFR
Hydrochloric Acid SCHEMBL7460964 0.80 BCHE (0.42) MEN1KMT2AKDM4EMAPTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963982-B1 New diaminobenzene derivatives and these componends containing colouring agents WELLA AG (DE) 2002-03-13 EP claimed
US-6132475-A FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS WELLA AKTIENGESELLSCHAFT (DE) 2000-10-17 US claimed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP claimed
EP-0963982-B1 New diaminobenzene derivatives and these componends containing colouring agents WELLA AG (DE) 2002-03-13 EP disclosed
US-6132475-A FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS WELLA AKTIENGESELLSCHAFT (DE) 2000-10-17 US disclosed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP disclosed