Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314835 | 0.88 | SLC6A3 (0.48) | — | |
| SCHEMBL8602315 | 0.88 | SLC6A3 (0.48) | — | |
| SCHEMBL8602312 | 0.88 | SLC6A3 (0.48) | — | |
| SCHEMBL7314846 | 0.88 | SLC6A3 (0.48) | — | |
| SCHEMBL7421806 | 0.88 | SLC6A3 (0.48) | — | |
| SCHEMBL7246774 | 0.85 | SLC6A3 (0.42) | — | |
| SCHEMBL7241761 | 0.85 | SLC6A3 (0.42) | — | |
| SCHEMBL8604270 | 0.84 | SLC6A2 (0.43) | — | |
| SCHEMBL8604267 | 0.84 | SLC6A2 (0.43) | — | |
| SCHEMBL6598452 | 0.78 | CYP2D6 (0.46) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | disclosed |
| US-5328917-A | Aminoalkyl and phenyl substituted hydrogenated pyridines | NOVO NORDISK A/S (DK) | 1994-07-12 | — | — | US | disclosed |
| EP-0558487-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |