Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604270 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3LMNAMAPT | |
| SCHEMBL8602312 | 0.91 | SLC6A3 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7314835 | 0.91 | SLC6A3 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8602315 | 0.91 | SLC6A3 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7421806 | 0.91 | SLC6A3 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7314846 | 0.91 | SLC6A3 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7241761 | 0.88 | SLC6A3 (0.42) | SLC6A3 | |
| SCHEMBL7246774 | 0.88 | SLC6A3 (0.42) | SLC6A3 | |
| SCHEMBL7461306 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL8606660 | 0.82 | SLC6A3 (0.45) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339579-B1 | Piperidine compositions and their preparation and use | NOVO NORDISK AS (DK) | 1998-07-15 | — | — | EP | disclosed |
| US-5227379-A | 1-Heterocycyl-4-phenyl substituted, calcium-channel antagonists | NOVO NORDISK A/S (DK) | 1993-07-13 | — | — | US | disclosed |
| US-5208232-A | Anoxia, migraine; antiepileptic and antiischemic agents | NOVO NORDISK A/S (DK) | 1993-05-04 | — | — | US | disclosed |
| US-5158961-A | Treatment of anoxia, migraine, ischemica and epilepsy | NOVO NORDISK A/S (DK) | 1992-10-27 | — | — | US | disclosed |
| US-5017585-A | Piperidine compounds | NOVO NORDISK A/S (DK) | 1991-05-21 | — | — | US | disclosed |
| EP-0339579-A2 | Piperidine compositions and their preparation and use | NOVO NORDISK A/S (DK) | 1989-11-02 | — | — | EP | disclosed |