Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529202 | 0.86 | NR4A2 (0.59) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL7464868 | 0.85 | MAPT (0.54) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL7464969 | 0.83 | APP (0.49) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL7461008 | 0.83 | NPC1 (0.58) | LMNASMN1; SMN2APPMAPTALDH1A1 | |
| SCHEMBL7468141 | 0.83 | APP (0.49) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL7466204 | 0.83 | APP (0.49) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL7458619 | 0.83 | APP (0.52) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL27312782 | 0.83 | APP (0.49) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL7461222 | 0.83 | APP (0.55) | LMNASMN1; SMN2APPMAPTHPGD | |
| SCHEMBL4472632 | 0.82 | KDM4E (0.43) | LMNASMN1; SMN2MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |