Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529202 | 0.89 | NR4A2 (0.59) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL27312782 | 0.85 | APP (0.49) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL7461008 | 0.85 | NPC1 (0.58) | MAPTAPPLMNASMN1; SMN2POLB | |
| SCHEMBL7461560 | 0.85 | LMNA (0.51) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL7464969 | 0.85 | APP (0.49) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL7458619 | 0.85 | APP (0.52) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL7468141 | 0.85 | APP (0.49) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL7466204 | 0.85 | APP (0.49) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL7461222 | 0.85 | APP (0.55) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL7456842 | 0.84 | LMNA (0.47) | MAPTKMT2AMEN1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| CN-1031263-C | Quinoline, quinazoline, and cinnoline | LILLY CO ELI (US) | 1996-03-13 | — | — | CN | disclosed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | disclosed |
| CN-1034925-A | Quinoline, quinazoline and cinnoline | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |
| EP-0326330-A2 | Quinoline, quinazoline, and cinnoline fungicides | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |