Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460207 | 0.92 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4EPPARG | |
| SCHEMBL7462587 | 0.90 | PPARG (0.30) | PPARG | |
| SCHEMBL7462094 | 0.87 | ALDH2 (0.34) | ALDH2POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7461938 | 0.87 | PPARG (0.36) | ALDH2POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7458117 | 0.85 | POLB (0.36) | ALDH2POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7465907 | 0.84 | KDM4E (0.39) | POLBALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7467977 | 0.84 | — | — | |
| SCHEMBL7465310 | 0.81 | PPARG (0.34) | ALDH2POLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7460017 | 0.80 | ALDH1A1 (0.32) | POLBSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL8096320 | 0.80 | PPARG (0.37) | ALDH1A1HPGDKDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |