Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460207 | 0.88 | ALDH1A1 (0.39) | PPARGTDP1KDM4EALDH1A1HPGD | |
| SCHEMBL7463612 | 0.88 | AGER (0.35) | TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL8096316 | 0.87 | PPARG (0.40) | PPARG | |
| SCHEMBL7461945 | 0.80 | ALDH2 (0.38) | PPARGKDM4EALDH1A1HPGD | |
| SCHEMBL8093870 | 0.79 | TDP1 (0.34) | PPARGTDP1KDM4EALDH1A1HPGD | |
| SCHEMBL7462587 | 0.78 | PPARG (0.30) | PPARG | |
| SCHEMBL7462094 | 0.77 | ALDH2 (0.34) | PPARGKDM4EALDH1A1HPGD | |
| SCHEMBL7467977 | 0.77 | — | — | |
| SCHEMBL7463605 | 0.77 | PTGDR2 (0.37) | PPARGKDM4EALDH1A1 | |
| SCHEMBL7457336 | 0.77 | NPC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156700-A | 3-(1,2-Benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione herbicidal agents | AMERICAN CYANMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |