Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344262 | 0.80 | HRH3 (0.40) | HRH3 | |
| SCHEMBL7350177 | 0.76 | HRH4 (0.43) | ACACBHRH3 | |
| SCHEMBL7342864 | 0.76 | PARP1 (0.40) | HRH3 | |
| SCHEMBL7367199 | 0.75 | PARP1 (0.38) | HRH3 | |
| SCHEMBL7340536 | 0.75 | OGA (0.45) | HRH3 | |
| Bicarbonate SCHEMBL7341736 | 0.69 | GBA1 (0.36) | ACACBGBA1 | |
| SCHEMBL7344255 | 0.68 | HRH3 (0.42) | HRH3 | |
| SCHEMBL7341730 | 0.68 | KDM4E (0.35) | ACACBGBA1 | |
| SCHEMBL7581624 | 0.67 | — | — | |
| SCHEMBL7348379 | 0.67 | OGA (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |